Structure of PDB 3tzz Chain B Binding Site BS01

Receptor Information
>3tzz Chain B (length=465) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PGVTEEALRLKEAALEELAAQEVTAPLVPLAVSAFLTSRKKAAAAELADW
MQSPEGQASSLESIGRSLSRRNHGRSRAVVLAHDHDEAIKGLRAVAAGKQ
APNVFSVDGPVTTGPVWVLAGFGAQHRKMGKSLYLRNEVFAAWIEKVDAL
VQDELGYSVLELILDDAQDYGIETTQVTIFAIQIALGELLRHHGAKPAAV
IGQSLGEAASAYFAGGLSLRDATRAICSRSHLMGEGEAMLFGEYIRLMAL
VEYSADEIREVFSDFPDLEVCVYAAPTQTVIGGPPEQVDAILARAEAEGK
FARKFATKGASHTSQMDPLLGELTAELQGIKPTSPTCGIFSTVHEGRYIK
PGGEPIHDVEYWKKGLRHSVYFTHGIRNAVDSGHTTFLELAPNPVALMQV
ALTTADAGLHDAQLIPTLARKQDEVSSMVSTMAQLYVYGHDLDIRTLFSR
ASGPQDYANIPPTRF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3tzz Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13
Resolution2.49 Å
Binding residue
(original residue number in PDB)		L624 L678 H680 P699 N700 F702 P1013 Q1019 S1027
Binding residue
(residue number reindexed from 1)		L27 L81 H83 P102 N103 F105 P416 Q422 S430
Enzymatic activity
Catalytic site (original residue number in PDB) S801 L802 R826 H909 G962
Catalytic site (residue number reindexed from 1) S204 L205 R229 H312 G365
Enzyme Commision number 2.3.1.-
Gene Ontology
Molecular Function
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:3tzz, PDBe:3tzz, PDBj:3tzz
PDBsum3tzz
PubMed22825853
UniProtO53579

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