Structure of PDB 3tu5 Chain B Binding Site BS01

Receptor Information
>3tu5 Chain B (length=132) Species: 9606,10090 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTV
QLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQG
FESATFLGYFKSGLKYKKGGVASKLRKVAEQT
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3tu5 Chain B Residue 326 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3tu5 Structural States and dynamics of the d-loop in actin.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		G41 D42 E73 V121
Binding residue
(residue number reindexed from 1)		G41 D42 E73 V121
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0003785 actin monomer binding
GO:0051015 actin filament binding
Biological Process
GO:0007015 actin filament organization

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Molecular Function
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Biological Process
External links
PDB RCSB:3tu5, PDBe:3tu5, PDBj:3tu5
PDBsum3tu5
PubMed23009842
UniProtP06396|GELS_HUMAN Gelsolin (Gene Name=GSN);
P62328;
Q5NBX1

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