Structure of PDB 3toc Chain B Binding Site BS01

Receptor Information
>3toc Chain B (length=217) Species: 301447 (Streptococcus pyogenes serotype M1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TMNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYQYESELKFFDHKM
KTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLV
ATITELIVFECLENELDLEYDEITILELIKSLGVKVETSDTIFEKCLEIL
QIFKYLTKKKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRELYD
FPQYILDEDYFLITKNM
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3toc Chain B Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3toc Crystal Structure of Streptococcus pyogenes Csn2 Reveals Calcium-Dependent Conformational Changes in Its Tertiary and Quaternary Structure
Resolution2.201 Å
Binding residue
(original residue number in PDB)		D122 E123 E128
Binding residue
(residue number reindexed from 1)		D121 E122 E127
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:3toc, PDBe:3toc, PDBj:3toc
PDBsum3toc
PubMed22479393
UniProtQ99ZV9|CSN2_STRP1 CRISPR-associated protein Csn2 (Gene Name=csn2)

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