Structure of PDB 3tm7 Chain B Binding Site BS01

Receptor Information
>3tm7 Chain B (length=94) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVAGA
AAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTA
Ligand information
>3tm7 Chain A (length=26) Species: 83333 (Escherichia coli K-12) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GSMIRTMLQGKLHRVKVTHADLHYEG
Receptor-Ligand Complex Structure
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PDB3tm7 Structure of Escherichia coli aspartate alpha-decarboxylase Asn72Ala: probing the role of Asn72 in pyruvoyl cofactor formation
Resolution1.7 Å
Binding residue
(original residue number in PDB)		A36 G37 I68 I69 S70 V71 A72 G73 H77 S80 V81 G82 D83 I84 V85 I86 I87 A88 S89 F90 V91 T92 M93 P94 D95 A98 W101 P103 N104 V105 A106 F108 N112
Binding residue
(residue number reindexed from 1)		A12 G13 I44 I45 S46 V47 A48 G49 H53 S56 V57 G58 D59 I60 V61 I62 I63 A64 S65 F66 V67 T68 M69 P70 D71 A74 W77 P79 N80 V81 A82 F84 N88
Enzymatic activity
Catalytic site (original residue number in PDB) S25 Y58
Catalytic site (residue number reindexed from 1) S1 Y34
Enzyme Commision number 4.1.1.11: aspartate 1-decarboxylase.
Gene Ontology
Molecular Function
GO:0004068 aspartate 1-decarboxylase activity
Biological Process
GO:0006523 alanine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3tm7, PDBe:3tm7, PDBj:3tm7
PDBsum3tm7
PubMed22505409
UniProtP0A790|PAND_ECOLI Aspartate 1-decarboxylase (Gene Name=panD)

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