Structure of PDB 3tfc Chain B Binding Site BS01

Receptor Information

>3tfc Chain B (length=330) Species: 169963 (Listeria monocytogenes EGD-e) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NLEELRTQVDQLNIDLLELISKRANLVQEREMLNTILAANEGPFEDSTVQ
KLFKEIFKAGLHSKALLVSRKNKKEDTIVTVKGLPIGNGEPVFVFGPCSV
ESYEQVAAVAESIKAKGLKLIRGGAFKPRTSPYDFQGLGLEGLKILKRVS
DEYGLGVISEIVTPADIEVALDYVDVIQIGARNMQNFELLKAAGRVDKPI
LLKRGLSATIEEFIGAAEYIMSQGNGKIILCERGIRTYEKATRNTLDISA
VPILKKETHLPVMVDVTHSTGRKDLLLPCAKAALAIEADGVMAEVHPDPA
VALSDSAQQMDIPEFEEFWNAILASNLVPH

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

3tfc Chain B Residue 362 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3tfc Structural analysis of a 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with an N-terminal chorismate mutase-like regulatory domain.
Resolution	1.95 Å
Binding residue (original residue number in PDB)	C126 H296 E322 D333
Binding residue (residue number reindexed from 1)	C98 H268 E294 D305
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0016832	aldehyde-lyase activity
GO:0046872	metal ion binding

	Biological Process
GO:0009058	biosynthetic process
GO:0009073	aromatic amino acid family biosynthetic process
GO:0046417	chorismate metabolic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:3tfc, PDBe:3tfc, PDBj:3tfc
PDBsum	3tfc
PubMed	22505283
UniProt	Q8Y6T2

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