Structure of PDB 3tcf Chain B Binding Site BS01

Receptor Information
>3tcf Chain B (length=517) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVS
DLDGHPAPGVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRS
VDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSE
PVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVNE
RIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPI
ELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD
IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAE
AGYTADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTF
LDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIM
AETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTG
KDPLDNTYTRNMYIVKH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3tcf Escherichia coli peptide binding protein OppA has a preference for positively charged peptides.
Resolution2.0 Å
Binding residue
(original residue number in PDB)
E58 G59 V60 Y135 W423 R439 G441 W442 C443 D445
Binding residue
(residue number reindexed from 1)
E32 G33 V34 Y109 W397 R413 G415 W416 C417 D419
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:1900750 oligopeptide binding
GO:1904680 peptide transmembrane transporter activity
Biological Process
GO:0006857 oligopeptide transport
GO:0009408 response to heat
GO:0015031 protein transport
GO:0015833 peptide transport
GO:0055085 transmembrane transport
GO:0061077 chaperone-mediated protein folding
GO:0140205 oligopeptide import across plasma membrane
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:3tcf, PDBe:3tcf, PDBj:3tcf
PDBsum3tcf
PubMed21983341
UniProtP23843|OPPA_ECOLI Periplasmic oligopeptide-binding protein OppA (Gene Name=oppA)

[Back to BioLiP]