Structure of PDB 3t6r Chain B Binding Site BS01
Receptor Information
>3t6r Chain B (length=68) Species:
9606
(Homo sapiens) [
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EFGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLD
PPLSSVPSEDEWYCPECR
Ligand information
>3t6r Chain D (length=5) Species:
9606
(Homo sapiens) [
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ARTKQ
Receptor-Ligand Complex Structure
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PDB
3t6r
UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail
Resolution
1.95 Å
Binding residue
(original residue number in PDB)
P327 Q330 L331 M332 C333 D334 D337 E355
Binding residue
(residue number reindexed from 1)
P31 Q34 L35 M36 C37 D38 D41 E59
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:3t6r
,
PDBe:3t6r
,
PDBj:3t6r
PDBsum
3t6r
PubMed
22100450
UniProt
Q96T88
|UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (Gene Name=UHRF1)
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