Structure of PDB 3rtx Chain B Binding Site BS01

Receptor Information
>3rtx Chain B (length=254) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLKLGAIFLEGITVKGVTQVTTQPKLGEVQQKCHQFCGWEGSGFPGAQPV
SMDKQNIRLLEQKPYKVSWKADGTRYMMLIDGTNEVFMIDRDNSVFHVSN
LEFPFRKDLRMHLSNTLLDGEMIIDKVNGQAVPRYLIYDIIKFNAQPVGD
CDFNIRLQCIEREIISPRHEKMKTGLIDKTQEPFSVRPKQFFDINISRKL
LEGNMDGLIFQPIGKYKPGRCDDILKWKPPSLCNSISNPVTKEMLFEFID
RCAA
Ligand information
Receptor-Ligand Complex Structure
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PDB3rtx Structural insights to how mammalian capping enzyme reads the CTD code.
Resolution2.81 Å
Binding residue
(original residue number in PDB)		R330 C375 C383 E387
Binding residue
(residue number reindexed from 1)		R106 C151 C159 E163
Enzymatic activity
Enzyme Commision number 2.7.7.50: mRNA guanylyltransferase.
3.6.1.74: mRNA 5'-phosphatase.
Gene Ontology
Molecular Function
GO:0004484 mRNA guanylyltransferase activity
GO:0005524 ATP binding
Biological Process
GO:0006370 7-methylguanosine mRNA capping

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Molecular Function
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Biological Process
External links
PDB RCSB:3rtx, PDBe:3rtx, PDBj:3rtx
PDBsum3rtx
PubMed21683636
UniProtO55236|MCE1_MOUSE mRNA-capping enzyme (Gene Name=Rngtt)

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