Structure of PDB 3rma Chain B Binding Site BS01

Receptor Information
>3rma Chain B (length=897) Species: 12353 (Escherichia phage RB69) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKEFYLTVEQIGDSIFERYIDSNGRERTREVEYKPSLFAHCPESQATKYF
DIYGKPCTRKLFANMRDASQWIKRMEDIGLEALGMDDFKLAYLSDTYNYE
IKYDHTKIRVANFDIEVTSPDGFPEPSQAKHPIDAITHYDSIDDRFYVFD
LLNSPYGNVEEWSIEIAAKLQEQGGDEVPSEIIDKIIYMPFDNEKELLME
YLNFWQQKTPVILTGWNVESFAIPYVYNRIKNIFGESTAKRLSPHRKTRV
KVIREIITLFGISVLDYIDLYKKFSFTNQPSYSLDYISEFELNVGKLKYD
GPISKLRESNHQRYISYNIIAVYRVLQIDAKRQFINLSLDMGYYAKIQIQ
SVFSPIKTWDAIIFNSLKEQNKVIPQGRSHPVQPYPGAFVKEPIPNRYKY
VMSFDLTSLYPSIIRQVNISPETIAGTFKVAPLHDYINAVAERPSDVYSC
SPNGMMYYKDRDGVVPTEITKVFNQRKEHKGYMLAAQRNGEIIKEALHNP
NLSVDEPLDVDYRFDFSDEIKEKIKKLSAKSLNEMLFRAQRTEVAGMTAQ
INRKLLINSLYGALGNVWFRYYDLRNATAITTFGQMALQWIERKVNEYLN
EVCGTEGEAFVLYGDTDSIYVSADKIIDKVGESKFRDTNHWVDFLDKFAR
ERMEPAIDRGFREMCEYMNNKQHLMFMDREAIAGPPLGSKGIGGFWTGKK
RYALNVWDMEGTRYAEPKLKIMGLETQKSSTPKAVQKALKECIRRMLQEG
EESLQEYFKEFEKEFRQLNYISIASVSSANNIAKYDVGGFPGPKCPFHIR
GILTYNRAIKGNIDAPQVVEGEKVYVLPLREGNPFGDKCIAWPSGTEITD
LIKDDVLHWMDYTVLLEKTFIKPLEGFTSAAKLDYEKKASLFDMFDF
Ligand information
Receptor-Ligand Complex Structure
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PDB3rma A crystallographic study of the role of sequence context in thymine glycol bypass by a replicative DNA polymerase serendipitously sheds light on the exonuclease complex.
Resolution2.84 Å
Binding residue
(original residue number in PDB)		K705 R707 C801 F803 K878
Binding residue
(residue number reindexed from 1)		K699 R701 C795 F797 K872
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:3rma, PDBe:3rma, PDBj:3rma
PDBsum3rma
PubMed21781974
UniProtQ38087|DPOL_BPR69 DNA-directed DNA polymerase (Gene Name=43)

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