Structure of PDB 3rek Chain B Binding Site BS01

Receptor Information
>3rek Chain B (length=83) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDA
VTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Ligand information
>3rek Chain I (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atctccaaatatcccttgcggatcgtagaaaaagtgtgtcaaactgcgct
atcaaagggaaacttcaactgaattcagttgaagtttccctttgatagcg
cagtttgacacactttttctacgatccgcaagggatatttggagat
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3rek Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
T30 P32 R36 R45
Binding residue
(residue number reindexed from 1)
T11 P13 R17 R26
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:3rek, PDBe:3rek, PDBj:3rek
PDBsum3rek
PubMed21724603
UniProtP62799|H4_XENLA Histone H4

[Back to BioLiP]