Structure of PDB 3r8f Chain B Binding Site BS01

Receptor Information
>3r8f Chain B (length=319) Species: 63363 (Aquifex aeolicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DFLNPKYTLENFIVGEGNRLAYEVVKEALENLGSLYNPIFIYGSVGTGKT
HLLQAAGNEAKKRGYRVIYSSADDFAQAMVEHLKKGTINEFRNMYKSVDL
LLLDDVQFLSGKERTQIEFFHIFNTLYLLEKQIILASDRHPQKLDGVSDR
LVSRFEGGILVEIELDNKTRFKIIKEKLKEFNLELRKEVIDYLLENTKNV
REIEGKIKLIKLKGFEGLERKERKERDKLMQIVEFVANYYAVKVEDILSD
KNKRTSEARKIAMYLCRKVCSASLIEIARAFKRKDHTTVIHAIRSVEEEK
RKFKHLVGFLEKQAFDKIC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3r8f DNA stretching by bacterial initiators promotes replication origin opening.
Resolution3.366 Å
Binding residue
(original residue number in PDB)		K188 E189 R190 T191
Binding residue
(residue number reindexed from 1)		K112 E113 R114 T115
Binding affinityPDBbind-CN: Kd=0.11uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006270 DNA replication initiation
GO:0006275 regulation of DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:3r8f, PDBe:3r8f, PDBj:3r8f
PDBsum3r8f
PubMed21964332
UniProtO66659|DNAA_AQUAE Chromosomal replication initiator protein DnaA (Gene Name=dnaA)

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