Structure of PDB 3qnw Chain B Binding Site BS01

Receptor Information
>3qnw Chain B (length=93) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELL
TLVNRKVSQRRVDFCKDPSAIGKKQVPCFASMLTKKLHFFPKS
Ligand information
Receptor-Ligand Complex Structure
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PDB3qnw Structure of human caspase-6 in complex with Z-VAD-FMK: New peptide binding mode observed for the non-canonical caspase conformation.
Resolution2.65 Å
Binding residue
(original residue number in PDB)		E214 G215 Y216 Y217 S218 H219 W227 A269 K272 K273
Binding residue
(residue number reindexed from 1)		E15 G16 Y17 Y18 S19 H20 W28 A70 K73 K74
Enzymatic activity
Enzyme Commision number 3.4.22.59: caspase-6.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3qnw, PDBe:3qnw, PDBj:3qnw
PDBsum3qnw
PubMed21820899
UniProtP55212|CASP6_HUMAN Caspase-6 (Gene Name=CASP6)

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