Structure of PDB 3qni Chain B Binding Site BS01

Receptor Information
>3qni Chain B (length=266) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDSFWEVGNYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAK
RWRQLIEKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKN
WQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACK
EEKLAMDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEE
KRLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWFRS
TSGPGMPMNWPQFEEW
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3qni Chain B Residue 400 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3qni Crystal structure of human PACSIN 1 F-BAR domain
Resolution2.8 Å
Binding residue
(original residue number in PDB)		I71 E72 G74 Q76 E81
Binding residue
(residue number reindexed from 1)		I56 E57 G59 Q61 E66
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007015 actin filament organization
GO:0048666 neuron development
GO:0097320 plasma membrane tubulation

View graph for
Biological Process
External links
PDB RCSB:3qni, PDBe:3qni, PDBj:3qni
PDBsum3qni
PubMed
UniProtQ9BY11|PACN1_HUMAN Protein kinase C and casein kinase substrate in neurons protein 1 (Gene Name=PACSIN1)

[Back to BioLiP]