Structure of PDB 3qhr Chain B Binding Site BS01

Receptor Information
>3qhr Chain B (length=261) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNEVPDYQEDIHTYLREMEVKCKPKVGYMKRQPDITNSMRAILVDWLVEV
GEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIY
PPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFDLAAPTVNQFLTQYFLH
LQPANCKVESLAMFLGELSLIDADPYLKYLPSLIAGAAFHLALYTVTGQS
WPESLAQQTGYTLESLKPCLVDLHQTYLKAPQHAQQSIREKYKHSKYHSV
SLLNPPETLSV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3qhr Briefly Bound to Activate: Transient Binding of a Second Catalytic Magnesium Activates the Structure and Dynamics of CDK2 Kinase for Catalysis.
Resolution2.17 Å
Binding residue
(original residue number in PDB)
I270 Y271
Binding residue
(residue number reindexed from 1)
I99 Y100
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:3qhr, PDBe:3qhr, PDBj:3qhr
PDBsum3qhr
PubMed21565702
UniProtP51943|CCNA2_MOUSE Cyclin-A2 (Gene Name=Ccna2)

[Back to BioLiP]