Structure of PDB 3qfq Chain B Binding Site BS01
Receptor Information
>3qfq Chain B (length=120) Species:
493803
(Merkel cell polyomavirus) [
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TPVPTDFPIDLSDYLSHAVYSNKTVSCFAIYTTSDKAIELYDKIEKFKVD
FKSRHACELGCILLFITLSKHRVSAIKNFCSTFCTISFLICKGVNKMPEM
YNNLCKPPYKLLQENKPLLN
Ligand information
>3qfq Chain W (length=26) [
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gcagaggcttggggctcctagcctcc
Receptor-Ligand Complex Structure
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PDB
3qfq
Asymmetric assembly of merkel cell polyomavirus large T-antigen origin binding domains at the viral origin.
Resolution
2.9001 Å
Binding residue
(original residue number in PDB)
T332 K378 H379 R380 A383
Binding residue
(residue number reindexed from 1)
T24 K70 H71 R72 A75
Binding affinity
PDBbind-CN
: Kd=741nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003688
DNA replication origin binding
Biological Process
GO:0006260
DNA replication
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Molecular Function
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Biological Process
External links
PDB
RCSB:3qfq
,
PDBe:3qfq
,
PDBj:3qfq
PDBsum
3qfq
PubMed
21501625
UniProt
E2IPT4
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