Structure of PDB 3q47 Chain B Binding Site BS01

Receptor Information
>3q47 Chain B (length=132) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLK
MQQPEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYS
LAKEQRLNFGDDIPSALRIAKKKRWNSIEERR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3q47 Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
Resolution1.705 Å
Binding residue
(original residue number in PDB)		K31 N35 N66 L69 K96 F99 F132 D135 I136
Binding residue
(residue number reindexed from 1)		K8 N12 N43 L46 K73 F76 F109 D112 I113
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:3q47, PDBe:3q47, PDBj:3q47
PDBsum3q47
PubMed21454478
UniProtQ9WUD1|CHIP_MOUSE E3 ubiquitin-protein ligase CHIP (Gene Name=Stub1)

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