Structure of PDB 3q0o Chain B Binding Site BS01

Receptor Information
>3q0o Chain B (length=335) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAE
RQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLEQKLALAERIRGHVLS
LALQMYGCRVIQKALEFIPSDQQNEMVRELDGHVLKCVKDQNGNHVVQKC
IECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILE
ELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKF
ASNVVEKCVTHASRTERAVLIDEVCTSALYTMMKDQYANYVVQKMIDVAE
PGQRKIVMHKIRPHIATLRKYTYGKHILAKLEKYY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3q0o Alternate modes of cognate RNA recognition by human PUMILIO proteins.
Resolution2.804 Å
Binding residue
(original residue number in PDB)
N899 Y900 Y933 R936 Q939 H972 R1008 Q1011 N1043 Y1044 K1076 F1077 N1080 E1083 Y1120 N1122 Y1123 Q1126 Y1156 H1159
Binding residue
(residue number reindexed from 1)
N72 Y73 Y106 R109 Q112 H145 R181 Q184 N216 Y217 K249 F250 N253 E256 Y287 N289 Y290 Q293 Y323 H326
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3q0o, PDBe:3q0o, PDBj:3q0o
PDBsum3q0o
PubMed21397187
UniProtQ14671|PUM1_HUMAN Pumilio homolog 1 (Gene Name=PUM1)

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