Structure of PDB 3q0m Chain B Binding Site BS01

Receptor Information
>3q0m Chain B (length=338) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAERQ
LVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLEQKLALAERIRGHVLSLA
LQMYGCRVIQKALEFIPSDQQNEMVRELDGHVLKCVKDQNGNHVVQKCIE
CVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEEL
HQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKFAS
NVVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQKMI
DVAEPGQRKIVMHKIRPHIATLRKYTYGKHILAKLEKY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3q0m Alternate modes of cognate RNA recognition by human PUMILIO proteins.
Resolution2.705 Å
Binding residue
(original residue number in PDB)		Q860 R864 Q867 F897 N899 Y900 Q903 Y933 R936 Q939 Q968 H972 Q975 Y1005 R1008 N1043 Y1044 F1077 N1080 E1083 N1122 Y1123 Q1126 Y1156 H1159
Binding residue
(residue number reindexed from 1)		Q31 R35 Q38 F68 N70 Y71 Q74 Y104 R107 Q110 Q139 H143 Q146 Y176 R179 N214 Y215 F248 N251 E254 N293 Y294 Q297 Y327 H330
Binding affinityPDBbind-CN: Kd=0.63nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3q0m, PDBe:3q0m, PDBj:3q0m
PDBsum3q0m
PubMed21397187
UniProtQ14671|PUM1_HUMAN Pumilio homolog 1 (Gene Name=PUM1)

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