Structure of PDB 3p37 Chain B Binding Site BS01
Receptor Information
>3p37 Chain B (length=219) Species:
9606
(Homo sapiens) [
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HLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYG
LGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSL
MKKITLLKYFRNYMSEHLLKAGANITPRELARLPYLRTWFRTRSAIILHL
SNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKE
LASRLRYARTMVDKLLSSR
Ligand information
>3p37 Chain D (length=9) [
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FDPPLHSTA
Receptor-Ligand Complex Structure
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PDB
3p37
From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
Resolution
2.38 Å
Binding residue
(original residue number in PDB)
W414 V415 D416 Y417 D419 Y481 F482 Y485 H489 L490 L491 H538 K540
Binding residue
(residue number reindexed from 1)
W42 V43 D44 Y45 D47 Y109 F110 Y113 H117 L118 L119 H163 K165
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:3p37
,
PDBe:3p37
,
PDBj:3p37
PDBsum
3p37
PubMed
21472932
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
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