Structure of PDB 3ots Chain B Binding Site BS01

Receptor Information
>3ots Chain B (length=99) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQITLWQRPIVTIKIGGQLKEALLNTGADDTVLEEVNLPGRWKPKLIGGI
GGFVKVRQYDQVPIEICGHKVIGTVLVGPTPANVIGRNLMTQIGCTLNF
Ligand information
>3ots Chain P (length=7) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
QNYPIVQ
Receptor-Ligand Complex Structure
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PDB3ots Nine Crystal Structures Determine the Substrate Envelope of the MDR HIV-1 Protease.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		R8 L23 N25 G27 A28 D29 I47 G48
Binding residue
(residue number reindexed from 1)		R8 L23 N25 G27 A28 D29 I47 G48
Enzymatic activity
Catalytic site (original residue number in PDB) N25 T26 G27
Catalytic site (residue number reindexed from 1) N25 T26 G27
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3ots, PDBe:3ots, PDBj:3ots
PDBsum3ots
PubMed21394574
UniProtP35963|POL_HV1Y2 Gag-Pol polyprotein (Gene Name=gag-pol)

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