Structure of PDB 3og8 Chain B Binding Site BS01
Receptor Information
>3og8 Chain B (length=128) Species:
9606
(Homo sapiens) [
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MDKENKKLLCRKCKALACYTADVRVIEESHYTVLGDAFKECFVSRPHPKP
KQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATG
VQTLYSKWKDFHFEKIPFDPAEMSKLEH
Ligand information
>3og8 Chain C (length=14) [
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ggcgcgcgcgcgcc
..............
Receptor-Ligand Complex Structure
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PDB
3og8
Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
R811 K849 F853
Binding residue
(residue number reindexed from 1)
R11 K49 F53
Enzymatic activity
Enzyme Commision number
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:3og8
,
PDBe:3og8
,
PDBj:3og8
PDBsum
3og8
PubMed
20961956
UniProt
O95786
|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)
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