Structure of PDB 3o35 Chain B Binding Site BS01

Receptor Information
>3o35 Chain B (length=178) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDL
SKPEVEYDCDAPKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPV
PLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAE
FNEPDSEVANAGIKLENYFEELLKNLYP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3o35 TRIM24 links a non-canonical histone signature to breast cancer.
Resolution1.76 Å
Binding residue
(original residue number in PDB)
F924 N980
Binding residue
(residue number reindexed from 1)
F96 N152
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:3o35, PDBe:3o35, PDBj:3o35
PDBsum3o35
PubMed21164480
UniProtO15164|TIF1A_HUMAN Transcription intermediary factor 1-alpha (Gene Name=TRIM24)

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