Structure of PDB 3ng8 Chain B Binding Site BS01

Receptor Information
>3ng8 Chain B (length=87) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EYGYIVTDQKPLSLAAGVKLLEILAEHVHMSSGSFINIAVVGPALTFRIR
HNEQNLSLADVTQQAGLVKSELEAQTGLQILQTGVGQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3ng8 Chain B Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ng8 Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2.
Resolution1.35 Å
Binding residue
(original residue number in PDB)		E542 Q548
Binding residue
(residue number reindexed from 1)		E73 Q79
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0030141 secretory granule

View graph for
Cellular Component
External links
PDB RCSB:3ng8, PDBe:3ng8, PDBj:3ng8
PDBsum3ng8
PubMed18048354
UniProtQ16849|PTPRN_HUMAN Receptor-type tyrosine-protein phosphatase-like N (Gene Name=PTPRN)

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