Structure of PDB 3mlp Chain B Binding Site BS01

Receptor Information
>3mlp Chain B (length=332) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIE
RTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMT
KQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDR
FFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVH
NNSKHGRAATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVW
SELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPT
IDYGFQRLQKVIPRLPKEVILKRAADLVEALY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3mlp Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins
Resolution2.8 Å
Binding residue
(original residue number in PDB)
K64 S169 N174 N197 L199 G203 N204 P205 F233 H235 N236 N237 H240
Binding residue
(residue number reindexed from 1)
K29 S134 N139 N162 L164 G168 N169 P170 F198 H200 N201 N202 H205
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:3mlp, PDBe:3mlp, PDBj:3mlp
PDBsum3mlp
PubMed20876732
UniProtQ07802|COE1_MOUSE Transcription factor COE1 (Gene Name=Ebf1)

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