Structure of PDB 3llm Chain B Binding Site BS01

Receptor Information
>3llm Chain B (length=235) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVPWSPPQSNWNPWTSSNIDEGPLAFATPEQISMDLKNELMYQLEQDHDL
QAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDD
FIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESI
LPRPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLR
DVVQAYPEVRIVLMSATIDTSMFCEYFFNCPIIEV
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain3llm Chain B Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3llm Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		T418 E512
Binding residue
(residue number reindexed from 1)		T90 E184
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding
GO:0033679 3'-5' DNA/RNA helicase activity

View graph for
Molecular Function
External links
PDB RCSB:3llm, PDBe:3llm, PDBj:3llm
PDBsum3llm
PubMed20510246
UniProtQ08211|DHX9_HUMAN ATP-dependent RNA helicase A (Gene Name=DHX9)

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