Structure of PDB 3l25 Chain B Binding Site BS01
Receptor Information
>3l25 Chain B (length=123) Species:
128952
(Ebola virus - Mayinga, Zaire, 1976) [
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DISAKDLRNIMYDHLPGFGTAFHQLVQVICKLGKDSNSLDIIHAEFQASL
AEGDSPQCALIQITKRVPIFQDAAPPVIHIRSRGDIPRACQKSLRPVPPS
PKIDRGWVCVFQLQDGKTLGLKI
Ligand information
>3l25 Chain C (length=8) [
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cgcaugcg
........
Receptor-Ligand Complex Structure
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PDB
3l25
Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
I278 Q279 K282 R312 R322
Binding residue
(residue number reindexed from 1)
I61 Q62 K65 R95 R105
Binding affinity
PDBbind-CN
: Kd=500nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3l25
,
PDBe:3l25
,
PDBj:3l25
PDBsum
3l25
PubMed
20081868
UniProt
Q05127
|VP35_EBOZM Polymerase cofactor VP35 (Gene Name=VP35)
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