Structure of PDB 3kii Chain B Binding Site BS01

Receptor Information
>3kii Chain B (length=617) Species: 1665 (Arthrobacter globiformis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASPFRLASAGEISEVQGILRTAGLLGPEKRIAYLGVLDPARGAAEDRRFR
VFIHDVSGARPQEVTVSVTNGTVISAVELDTAATGELPVLEEEFEVVEQL
LATDERWLKALAARNLDVSKVRVAPLSAGVFEYAEERGRRILRGLAFVQD
FPEDSAWAHPVDGLVAYVDVVSKEVTRVIDTGVFPVPAEHGNYTDPELTG
PLRTTQKPISITQPEGPSFTVTGGNHIEWEKWSLDVGFDVREGVVLHNIA
FRDGDRLRPIINRASIAEMVVPYGDPSPIRSWQNYFDTGEYLVGQYANSL
ELGCDCLGDITYLSPVISDAFGNPREIRNGICMHEEDWGILAKHSDLWSG
INYTRRNRRMVISFFTTIGNYDYGFYWYLYLDGTIEFEAKATGVVFTSAF
PEGGSDNISQLAPGLGAPFHQHIFSARLDMAIDGFTNRVEEEDVVRQTMG
PGNERGNAFSRKRTVLTRESEAVREADARTGRTWIISNPESKNRLNEPVG
YKLHAHNQPTLLADPGSSIARRAAFATKDLWVTRYADDERYPTGDFVNQH
SGGAGLPSYIAQDRDIDGQDIVVWHTFGLTHFPRVEDWPIMPVDTVGFKL
RPEGFFDRSPVLDVPAN
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain3kii Chain B Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3kii AGAO 5-phenoxy-2,3-pentadienylamine complex
Resolution1.9 Å
Binding residue
(original residue number in PDB)		H431 H433 H592
Binding residue
(residue number reindexed from 1)		H420 H422 H581
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Y284 D298 Y382 H431 H433 H592
Catalytic site (residue number reindexed from 1) Y273 D287 Y371 H420 H422 H581
Enzyme Commision number 1.4.3.21: primary-amine oxidase.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0008131 primary methylamine oxidase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0048038 quinone binding
GO:0052595 aliphatic amine oxidase activity
Biological Process
GO:0009308 amine metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3kii, PDBe:3kii, PDBj:3kii
PDBsum3kii
PubMed
UniProtP46881|PAOX_ARTGO Phenylethylamine oxidase

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