Structure of PDB 3kfu Chain B Binding Site BS01

Receptor Information
>3kfu Chain B (length=376) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRVLVRDLKAHVGQEVELLGFLHWRRDLGRIQFLLLRDRSGVVQVVTGGL
KLPLPESALRVRGLVVENAKAPGGLEVQAKEVEVLSPALEPTPVEIPKEE
WRANPDTLLEYRYVTLRGEKARAPLKVQAALVRGFRRYLDRQDFTEIFTP
QLYKQIMVGVFERVYEVAPVWLNEYLSLDVEMGFIADEEDLMRLEEALLA
EMLEEALNTAGDEIRLLGATWPSFPQDIPRLTHAEAKRILKEELGYPVGQ
DLSEEAERLLGEYAKERWGSDWLFVTRYPRSVRPFYTYPEEDGTTRSFDL
LFRGLEITSGGQRIHRYEELLESLKAKGMDPEAFHGYLEVFKYGMPPHGG
FAIGAERLTQKLLGLPNVRYARAFPR
Ligand information
>3kfu Chain N (length=71) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uccgcgguagcucaggguagagcagccggcuguuaaccgguaggucgcag
guucgaguccugcccgcggag
<<<<<<<..<<<<......>>>>.<<<<<.......>>>>>.....<<<<
<.......>>>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB3kfu Crystal structure of a transfer-ribonucleoprotein particle that promotes asparagine formation.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		W24 R26 L28 G29 R30 I31 F33 Q44 K70 E76 P91 P93 E95 R102 N104 T107 Y111
Binding residue
(residue number reindexed from 1)		W24 R26 L28 G29 R30 I31 F33 Q44 K70 E76 P91 P93 E95 R102 N104 T107 Y111
Enzymatic activity
Catalytic site (original residue number in PDB) E345 S348 R396
Catalytic site (residue number reindexed from 1) E306 S309 R357
Enzyme Commision number 6.1.1.23: aspartate--tRNA(Asn) ligase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004815 aspartate-tRNA ligase activity
GO:0005524 ATP binding
GO:0050560 aspartate-tRNA(Asn) ligase activity
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006422 aspartyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0017101 aminoacyl-tRNA synthetase multienzyme complex

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Biological Process
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Cellular Component
External links
PDB RCSB:3kfu, PDBe:3kfu, PDBj:3kfu
PDBsum3kfu
PubMed20717102
UniProtQ5SIC2|SYDND_THET8 Aspartate--tRNA(Asp/Asn) ligase (Gene Name=aspS2)

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