Structure of PDB 3kd3 Chain B Binding Site BS01

Receptor Information

>3kd3 Chain B (length=216) Species: 119856 (Francisella tularensis subsp. tularensis)

MKNIIFDFDSTLIKKESLELILEPILQKSPAKLKEIEYITNLGMQGDISF
RDSLQKRLAIASPTKQSIKEFSNKYCPNLLTDGIKELVQDLKNKGFEIWI
FSGGLSESIQPFADYLNIPRENIFAVETIWNSDGSFKELDNSNGACDSKL
SAFDKAKGLIDGEVIAIGDGYTDYQLYEKGYATKFIAYMEHIEREKVINL
SKYVARNVAELASLIM

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3kd3 Chain B Residue 401

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3kd3 Crystal structure of a phosphoserine phosphohydrolase-like protein from Francisella tularensis subsp. tularensis SCHUS4
• Resolution: 1.7 Å
• Binding residue (original residue number in PDB): D7 D9 D169
• Binding residue (residue number reindexed from 1): D7 D9 D169
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): D7 F8 D9 G103 D173
• Catalytic site (residue number reindexed from 1): D7 F8 D9 G103 D173
• Enzyme Commision number: 3.1.3.3: phosphoserine phosphatase.

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0016787 hydrolase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006564 L-serine biosynthetic process
• GO:0016311 dephosphorylation

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:3kd3, PDBe:3kd3, PDBj:3kd3
• PDBsum: 3kd3
• UniProt: Q5NH99