Structure of PDB 3jap Chain B Binding Site BS01

Receptor Information
>3jap Chain B (length=222) Species: 28985 (Kluyveromyces lactis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VGKNKRLRVVDPFTRKEWYDIKAPSTFENRNVGKTLVNKSVGLKNASDSL
KGRVVEVCLADLQGSEDHSFRKVKLRVDEVQGKNLLTNFHGMDFTTDKLR
SMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRTSYAQSSHI
RQIRKVISEILTREVQNSTLAQLTSKLIPEVINKEIENATKDIFPLQNVH
IRKVKLLKQPKFDLGSLLSLHG
Ligand information
>3jap Chain 2 (length=1780) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacauggauaucug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacuccuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaacuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaguagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggucugguug
uccggucgguuuuucaaccggaucuuuccuucuggcuaaccuguacuccu
ugugggugcaggcgaaccaggacuuuuacuuugaaaaaauuagaguguuc
aaagcaggcgaaagcucgaauauauuagcauggaauaauggaauaggacg
uuugguucuauuuuguugguuucuaggaccaucguaaugauuaauaggga
cggucgggggcaucaguauucaauugucagaggugaaauucuuggauuua
uugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaauc
aagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucuua
accauaaacuaugccgacuagggaucgggugguguuuuucuuaugaccca
cucggcaccuuacgagaaaucaaagucuuuggguucuggggggaguaugg
ucgcaaggcugaaacuuaaaggaauugacggaagggcaccaccaggagug
gagccugcggcuuaauuugacucaacacggggaaacucaccagguccaga
cacaauaaggauugacagauugagagcucuuucuugauuuuguggguggu
ggugcauggccguucuuaguugguggagugauuugucugcuuaauugcga
uaacgaacgagaccuuaaccuacuaaauaggguugcuggcacuugccggu
ugacucuucuuagagggacuaucgguuucaagccgauggaaguuugaggc
aauaacaggucugugaugcccuuagacguucugggccgcacgcgcgcuac
acugacggagccagcgaguacaaccuuggccgagaggucuggguaaucuu
gugaaacuccgucgugcuggggauagagcauuguaauuauugcucuucaa
cgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacguccc
ugcccuuuguacacaccgcccgucgcuaguaccgauugaauggcuuagug
aggccucaggauuugcuuagagaagggggcaacuccaucucagagcgaag
aaucuggucaaacuuggucauuuagaggaacuaaaagucguaacaagguu
uccguaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[..((((((................[[[
.[[[..<<....<<....<<..........>>..>.>.>>......{{..
......[[[..{{..{.....[[[{...............<<.....<<.
<<.......>>.>>......>>........<<<<<..<<....>>..>>>
>>{..[[.((((......<<<<<<<<<<<....>>>..............
))))]].....}...<<<<..<<<.....>>>.>>>>..}.]]]....}}
}..]]].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<........
..>>>.>>...<<....>>.....]]]]]].........<<<....<<<.
....>>>..>>>...............<<<<<<<<<<<<......>>>>>
>>>>.>>>......<...<...........>...>.........<<<<<(
(....<.<<<<.........)).........>>>>>>>>>>..)))))).
]]].........[[[{{.......{{...[[[.[[....<.<<<<<<<<<
.....<..>.....>>>>>>>>>.>....<<<<<<....<.<<<.<<...
....>>.>>>.>....>>>>>>...<<<<<.<<.......<<...<....
...>..<<<....>.>>...>>......>>.>>..>>>.........[[.
..((((((((....>>>>>>>>.))))))))..]].....]]....<<<<
<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>......>.>
>>>>>..>>.......<<....>>...>>>>...>>>>>.>>>...]]].
..}}......<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>
>>..........<<<.<<.<<<..<<<<<<<<.<<.<.......>>>>>>
>>>>>..>>>...<<..}}>>...>>.....>>>.]]].<<<......<<
<<....>>>>....>>>..]]]]..<<<<<.<<<<<<<..<<.<<<<<<.
.<<<.<<<<<<......<<........>>..........<<<<<......
<<<<<........<<.<<<........>>>.>>......>>>>>...<<.
<<<..<<.<<<<<<....<<<.<<<<......>>...<<<......>>>.
..>>.>>>....<<<<..<<..<<<<..<<<<<<<<<<<<....>>>>>>
.>>>>>>..>>>>.>>....<<<<<<.....>>>>>>........>>>>.
...>>>.>>>.....>>>>>>>.......>>>>>...>>.>>>>.>>>..
...<<<<<<<......<<.....<.<..<<<....>>>...>>....>>.
......>>>>>>>......<.<..<<<<<<..........>>>>>>>...
>.....>>>>>>....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<.
.<<<<..<...<<<<<<..........................>>>>>>.
..>..>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<
<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3jap Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Resolution4.9 Å
Binding residue
(original residue number in PDB)		G4 N6 R8 L9 K27 R115 K116 W117 L120 R136 F138 Q146 N148 Q149 V150 K151 R152 Y155 Q157 S158 S159 H160 R165 K202 D203 I204 F205 P206 K216
Binding residue
(residue number reindexed from 1)		G2 N4 R6 L7 K16 R104 K105 W106 L109 R125 F127 Q135 N137 Q138 V139 K140 R141 Y144 Q146 S147 S148 H149 R154 K191 D192 I193 F194 P195 K205
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3jap, PDBe:3jap, PDBj:3jap
PDBsum3jap
PubMed26212456
UniProtQ6CWD0|RS3A_KLULA Small ribosomal subunit protein eS1 (Gene Name=RPS1)

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