Structure of PDB 3icf Chain B Binding Site BS01

Receptor Information

>3icf Chain B (length=315) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MSQEFISKMVNDLFLKGKYLPKKYVAAIISHADTLFRQEPSMVELENNST
PDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTYLFNGDFVDRGSWSCEV
ALLFYCLKILHPNNFFLNRGNHESDNMNKIYGFEDECKYKYSQRIFNMFA
QSFESLPLATLINNDYLVMHGGLPSDPSATLSDFKNIDRFAQPPRDGAFM
ELLWADPQEANGMGPSQRGHAFGPDITDRFLRNNKLRKIFRSHELRMGGV
QFEQKGKLMTVFSAPNYCDSQGNLGGVIHVVPGHGILQAGRNDDQNLIIE
TFEAVEHPDIKPMAY

Ligand information

Ligand ID

InChI

InChI=1S/Fe/q+3

InChIKey

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Name

FE (III) ION

PDB chain

3icf Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	3icf Structure of Protein serine/threonine phosphatase from Saccharomyces cerevisiae with similarity to human phosphatase PP5
Resolution	2.3 Å
Binding residue (original residue number in PDB)	D278 N310 H359 H434
Binding residue (residue number reindexed from 1)	D89 N121 H170 H243
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	D249 H251 D278 D281 R282 N310 H311 H359 R407 H434
Catalytic site (residue number reindexed from 1)	D60 H62 D89 D92 R93 N121 H122 H170 R218 H243
Enzyme Commision number	3.1.3.16: protein-serine/threonine phosphatase.

Gene Ontology

	Molecular Function
GO:0016787	hydrolase activity

View graph for
Molecular Function

External links

PDB	RCSB:3icf, PDBe:3icf, PDBj:3icf
PDBsum	3icf
PubMed
UniProt	P53043\|PPT1_YEAST Serine/threonine-protein phosphatase T (Gene Name=PPT1)

[Back to BioLiP]