Structure of PDB 3ibc Chain B Binding Site BS01

Receptor Information
>3ibc Chain B (length=92) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQI
LTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
Ligand information
Receptor-Ligand Complex Structure
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PDB3ibc Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		Y230 S231 W232 R233 P235 W240 S275 Q276
Binding residue
(residue number reindexed from 1)		Y19 S20 W21 R22 P24 W29 S64 Q65
Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3ibc, PDBe:3ibc, PDBj:3ibc
PDBsum3ibc
PubMed19655253
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

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