Structure of PDB 3i40 Chain B Binding Site BS01

Receptor Information
>3i40 Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKA
Ligand information
>3i40 Chain A (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB3i40 X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		V2 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 P28
Binding residue
(residue number reindexed from 1)		V2 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 P28
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:3i40, PDBe:3i40, PDBj:3i40
PDBsum3i40
PubMed20208155
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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