Structure of PDB 3hm1 Chain B Binding Site BS01

Receptor Information
>3hm1 Chain B (length=239) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR
ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKL
LFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII
LLNSGVYTFLKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL
SHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3hm1 Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and estrone ((8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthren-17-one)
Resolution2.33 Å
Binding residue
(original residue number in PDB)		I358 K362 L372 Q375 V376 E380 D538 E542
Binding residue
(residue number reindexed from 1)		I56 K60 L70 Q73 V74 E78 D227 E231
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3hm1, PDBe:3hm1, PDBj:3hm1
PDBsum3hm1
PubMed
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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