Structure of PDB 3h6z Chain B Binding Site BS01

Receptor Information

>3h6z Chain B (length=431) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GAMGSYDWLPRLSKENFNAAPVTCFPHAPGCEVWDNLGVGMKVEVETSFW
VATILEIKGYKALMSYEGFDTDSHDFWVNLCNAEVHSVGWCATRGKPLIP
PRTIEHKYKDWKDFLVGRLSGARTLPSNFYNKINDSLQSRFRLGLNLECV
DKDRISQVRLATVTKIVGDRLFLRYFDSDDGFWCHEDSPIIHPVGWATTV
GHNLAAPQDYLERMLAGREAMIEVHEDDATIELFKMNFTFDEYYSDGKTN
SFVEGMKLEAVDPLNLSSICPATVMAVLKFGYMMIRIDSYQPDASGSDWF
CYHEKSPCIFPAGFCSVNNISVTPPNGYDSRTFTWEGYLSDTGAVAAGQH
LFHDIIPDHGFEVGMSLECADLMDPRLVCVATVARVVGRLLKVHFDGWTD
EYDQWLDCESADIYPVGWCVLVNHKLEGPPR

Ligand information

>3h6z Chain M (length=6) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

HRKVLR

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3h6z Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt
Resolution	2.8 Å
Binding residue (original residue number in PDB)	D917 F941 W944 E947 Y948 K971 P976
Binding residue (residue number reindexed from 1)	D371 F395 W398 E401 Y402 K425 P430

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006355	regulation of DNA-templated transcription

	Cellular Component
GO:0005634	nucleus

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Biological Process

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Cellular Component

External links

PDB	RCSB:3h6z, PDBe:3h6z, PDBj:3h6z
PDBsum	3h6z
PubMed	19494831
UniProt	Q9VK33\|SMBT_DROME Polycomb protein Sfmbt (Gene Name=Sfmbt)

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