Structure of PDB 3guc Chain B Binding Site BS01

Receptor Information
>3guc Chain B (length=221) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDLSKVQAAEHTLR
NINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLSCVDNFE
ARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVVA
ANAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMSMK
PNPQCDDRNCRKQQEEYKKKV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3guc Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3guc Human Ubiquitin-activating Enzyme 5 in Complex with AMPPNP
Resolution2.25 Å
Binding residue
(original residue number in PDB)		C226 C229 C303 C308
Binding residue
(residue number reindexed from 1)		C140 C143 C205 C210
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0008641 ubiquitin-like modifier activating enzyme activity

View graph for
Molecular Function
External links
PDB RCSB:3guc, PDBe:3guc, PDBj:3guc
PDBsum3guc
PubMed
UniProtQ9GZZ9|UBA5_HUMAN Ubiquitin-like modifier-activating enzyme 5 (Gene Name=UBA5)

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