Structure of PDB 3gnn Chain B Binding Site BS01

Receptor Information

>3gnn Chain B (length=244) Species: 320372 (Burkholderia pseudomallei 1710b)

TIDAVSPLFADISREYGAAFDAAIARNVADALAEDVGSGDQAPRRARVIV
REDAVLCGVPWFDAVVRAVDPSIEVDWRHREGDRMSADSTVCELRGPARA
LLTAERNALNFLQLLSGVASATRQYVDRIADTRARILDTRKTLPGLRLAQ
KYAVRVGGGAVQIEVETLDQLRTALAHGARSVLLDNFTLDMMRDAVRVTE
GRAVLEVSGGVNFDTVRAIAETGVDRISIGALTKDVRATDYSMR

Ligand information

>3gnn Chain E (length=4) Species: 32644 (unidentified)

AAAA

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3gnn Crystal structure of nicotinate-nucleotide pyrophosphorylase from Burkholderi pseudomallei
• Resolution: 2.25 Å
• Binding residue (original residue number in PDB): R149 V208 Q209
• Binding residue (residue number reindexed from 1): R140 V161 Q162

Enzymatic activity

• Catalytic site (original residue number in PDB): R115 K150 E211 D232
• Catalytic site (residue number reindexed from 1): R106 K141 E164 D185
• Enzyme Commision number: 2.4.2.19: nicotinate-nucleotide diphosphorylase (carboxylating).

Gene Ontology

Molecular Function

• GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity
• GO:0016757 glycosyltransferase activity
• GO:0016763 pentosyltransferase activity

Biological Process

• GO:0009435 NAD biosynthetic process
• GO:0019363 pyridine nucleotide biosynthetic process
• GO:0034213 quinolinate catabolic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:3gnn, PDBe:3gnn, PDBj:3gnn
• PDBsum: 3gnn
• UniProt: Q3JV59