Structure of PDB 3gm1 Chain B Binding Site BS01

Receptor Information
>3gm1 Chain B (length=141) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IQPTANLDRTDDLVYLNVMELVRAVLELKNELAQLPPEGYVVVVKNVGLT
LRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVT
SLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPP
Ligand information
Receptor-Ligand Complex Structure
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PDB3gm1 Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2
Resolution2.95 Å
Binding residue
(original residue number in PDB)		T870 N872 M885 L892
Binding residue
(residue number reindexed from 1)		T4 N6 M19 L26
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Gene Ontology
Molecular Function
GO:0004713 protein tyrosine kinase activity
Biological Process
GO:0006468 protein phosphorylation
GO:0007172 signal complex assembly
Cellular Component
GO:0005925 focal adhesion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3gm1, PDBe:3gm1, PDBj:3gm1
PDBsum3gm1
PubMed19358827
UniProtQ14289|FAK2_HUMAN Protein-tyrosine kinase 2-beta (Gene Name=PTK2B)

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