Structure of PDB 3fha Chain B Binding Site BS01

Receptor Information
>3fha Chain B (length=583) Species: 37930 (Glutamicibacter protophormiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TYNGPLSSHWFPEELAQWEPDSDPDAPFNRSHVPLEPRVANRVNANADKD
AHLVSLSALNRHTSGVPSQGAPVFYENTFSYWHYTDLMVYWAGSAGEGII
VPPSADVIDASHRNGVPILGNVFFPPTVYGGQLEWLEQMLEQEEDGSFPL
ADKLLEVADYYGFDGWFINQETEGADEGTAEAMQAFLVYLQEQKPEGMHI
MWYDSMIDTGAIAWQNHLTDRNKMYLQNGSTRVADSMFLNFWWRDQRQSN
ELAQALGRSPYDLYAGVDVEARGTSTPVQWEGLFPEEKAHTSLGLYRPDW
AFQSSETMEAFYEKELQFWVGSTGNPAETDGQSNWPGMAHWFPAKSTATS
VPFVTHFNTGSGAQFSAEGKTVSEQEWNNRSLQDVLPTWRWIQHGGDLEA
TFSWEEAFEGGSSLQWHGSLAEGEHAQIELYQTELPLTWTFKSEHDNDLN
VGFRLDEEDFRYVEGEQRESINGWTQWTLQTITGLAFAAEGNGLAEFYTG
QLAVGSEKPAAPNVNVRQYDPDPSGIQLVWEKQSNVHHYRVYKEGKELIG
TSAGDRIYIEGLVRLHIEALSETFVPSDARMID
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3fha Chain B Residue 704 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3fha Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		A366 E377
Binding residue
(residue number reindexed from 1)		A363 E374
Annotation score1
Enzymatic activity
Enzyme Commision number 3.2.1.96: mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0033925 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006517 protein deglycosylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3fha, PDBe:3fha, PDBj:3fha
PDBsum3fha
PubMed19252736
UniProtQ9ZB22

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