Structure of PDB 3fde Chain B Binding Site BS01

Receptor Information
>3fde Chain B (length=206) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLV
LAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALN
CHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVV
KYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYL
EALANK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3fde UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
Resolution1.41 Å
Binding residue
(original residue number in PDB)		F437 R438 V451 A452 G453 A468 G470 Y471 D474 Y483 T484 S486 R496 K544
Binding residue
(residue number reindexed from 1)		F21 R22 V35 A36 G37 A52 G54 Y55 D58 Y67 T68 S70 R80 K128
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:3fde, PDBe:3fde, PDBj:3fde
PDBsum3fde
PubMed19077538
UniProtQ8VDF2|UHRF1_MOUSE E3 ubiquitin-protein ligase UHRF1 (Gene Name=Uhrf1)

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