Structure of PDB 3f73 Chain B Binding Site BS01 |
| >3f73 Chain B (length=670) Species: 262724 (Thermus thermophilus HB27)
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LGKTEVFLNRFALRPLNPEELRPWRLEVVLDPPPGREEVYPLLAQVARRA
GGVTVRMGDGLASWSPPEVLVLEGTLARMGQTYAYRLYPKGRRPLDPKDP
GERSVLSALARRLLQERLRRLEGVWVEGLAVYRREHARGPGWRVLGGAVL
DLWVSDSGAFLLEVDPAYRILCEMSLEAWLAQGHPLPKRVRNAYDRRTWE
LLRLGEEDPKELPLPGGLSLLDYHASKGRLQGREGGRVAWVADPKDPRKP
IPHLTGLLVPVLTLEDLHGSLALSLPWEERRRRTREIASWIGRRLGLGTP
EAVRAQAYRLSIPKLMGRRAVSKPADALRVGFYRAQETALALLRLDGAQG
WPEFLRRALLRAFGASGASLRLHTLHAHPSQGLAFREALRKAKEEGVQAV
LVLTPPMAWEDRNRLKALLLREGLPSQILNVPLREEERHRWENALLGLLA
KAGLQVVALSGYPAELAVGFDAGGRESFRFGGAACAVGGGHLLWTLPEAQ
AIPQEVVWDLLEETLWAFRRAGRLPSRVLLLRDGRVPQDEFALALEALAR
EGIAYDLVSVRKSGGGRVYPVQGRLADGLYVPLEDKTFLLLTVHRRGTPR
PLKLVHEAGDTPLEALAHQIFHLTRLYPASGFAFPRLPAPLHLADRLVKE
VGRLGIRHLKEVDREKLFFV |
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| PDB | 3f73 Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex. |
| Resolution | 3.0 Å |
Binding residue
(original residue number in PDB) | Q48 R52 A80 R81 M82 A170 Y171 R172 I173 R192 Y197 L217 Y226 H227 R232 I254 P255 V264 L279 S280 R286 M413 W415 R418 K422 Q433 I434 L435 N436 H445 R446 N449 R580 T613 P614 R615 A644 P650 R651 H657 |
Binding residue
(residue number reindexed from 1) | Q45 R49 A77 R78 M79 A167 Y168 R169 I170 R189 Y194 L214 Y223 H224 R229 I251 P252 V261 L273 S274 R280 M407 W409 R412 K416 Q427 I428 L429 N430 H439 R440 N443 R567 T598 P599 R600 A629 P635 R636 H642 |
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