Structure of PDB 3eyy Chain B Binding Site BS01

Receptor Information

>3eyy Chain B (length=133) Species: 1902 (Streptomyces coelicolor) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

STDWKSDLRQRGYRLTPQRQLVLEAVDTLEHATPDDILGEVRKTASGINI
STVYRTLELLEELGLVSHAHLGHGAPTYHLADRHHHIHLVCRDCTNVIEA
DLSVAADFTAKLREQFGFDTDMKHFAIFGRCES

Ligand information

InChI=1S/Ni/q+2

VEQPNABPJHWNSG-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ni++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ni+2]

Formula

Ni

Name

NICKEL (II) ION

PDB chain

3eyy Chain B Residue 146 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	3eyy Structural basis for the specialization of Nur, a nickel-specific Fur homolog, in metal sensing and DNA recognition
Resolution	2.4 Å
Binding residue (original residue number in PDB)	H70 H72 H126
Binding residue (residue number reindexed from 1)	H68 H70 H124
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000976	transcription cis-regulatory region binding
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0045892	negative regulation of DNA-templated transcription
GO:1900376	regulation of secondary metabolite biosynthetic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:3eyy, PDBe:3eyy, PDBj:3eyy
PDBsum	3eyy
PubMed	19336416
UniProt	Q9K4F8

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