Structure of PDB 3ehu Chain B Binding Site BS01

Receptor Information
>3ehu Chain B (length=441) Species: 9606,83333 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQV
AATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYN
GKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFN
LQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIK
NKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLG
AVALKSYEEELAKDPRIGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDE
ALKDAQTNAAAEFDQHCESLSLASNISGLQCNASVDLIGTCWPRSPAGQL
VVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQE
Ligand information
Receptor-Ligand Complex Structure
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PDB3ehu Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1.
Resolution1.96 Å
Binding residue
(original residue number in PDB)		I51 F72 Y73 V75 Y77 R96 V97 E104
Binding residue
(residue number reindexed from 1)		I388 F409 Y410 V412 Y414 R433 V434 E441
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0015144 carbohydrate transmembrane transporter activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ehu, PDBe:3ehu, PDBj:3ehu
PDBsum3ehu
PubMed18801728
UniProtP0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE);
P34998|CRFR1_HUMAN Corticotropin-releasing factor receptor 1 (Gene Name=CRHR1)

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