Structure of PDB 3e7c Chain B Binding Site BS01
Receptor Information
>3e7c Chain B (length=245) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
LPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAA
VKWAKAIPGFRNLHLDDQMTLLQYSWMYLMAFALGWRSYRQANLLCFAPD
LIINEQRMTLPGMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVP
KDGLKSQELFDEIRMTYIKELGKAIVKSQNWQRFYQLTKLLDSMHEVVEN
LLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ
Ligand information
>3e7c Chain D (length=10) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
NALLRYLLDK
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
3e7c
The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist.
Resolution
2.15 Å
Binding residue
(original residue number in PDB)
V575 K579 L589 Q592 M593 L596 Q597 M752 E755 N759
Binding residue
(residue number reindexed from 1)
V51 K55 L65 Q68 M69 L72 Q73 M221 E224 N228
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3e7c
,
PDBe:3e7c
,
PDBj:3e7c
PDBsum
3e7c
PubMed
18952422
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
[
Back to BioLiP
]
