Structure of PDB 3e44 Chain B Binding Site BS01

Receptor Information
>3e44 Chain B (length=241) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKVPFEKLVYKFLKENLSDLTFKQYEYLNDLFMK
NPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTADIL
LVKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKEFDLFDI
NYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLD
QGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3e44 DNA distortion and specificity in a sequence-specific endonuclease.
Resolution2.52 Å
Binding residue
(original residue number in PDB)
Q109 N110 D111 S144 Y146 K147 Q207
Binding residue
(residue number reindexed from 1)
Q93 N94 D95 S128 Y130 K131 Q191
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:3e44, PDBe:3e44, PDBj:3e44
PDBsum3e44
PubMed18762194
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

[Back to BioLiP]