Structure of PDB 3e43 Chain B Binding Site BS01

Receptor Information

>3e43 Chain B (length=240) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SFIKPIYQDINSILIGQKPFEKLVYKFLKENLSDLTFKQYEYLNDLFMKN
PAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTADILL
VKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKEFDLFDIN
YLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQ
GFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI

Ligand information

>3e43 Chain E (length=14) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gccggttaaccggc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3e43 DNA distortion and specificity in a sequence-specific endonuclease.
Resolution	2.73 Å
Binding residue (original residue number in PDB)	Q109 N110 K129 T130 F138 N141 S144 K147 A205
Binding residue (residue number reindexed from 1)	Q92 N93 K112 T113 F121 N124 S127 K130 A188

Enzymatic activity

Enzyme Commision number

3.1.21.4: type II site-specific deoxyribonuclease.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004519	endonuclease activity
GO:0009036	type II site-specific deoxyribonuclease activity

	Biological Process
GO:0009307	DNA restriction-modification system

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Molecular Function

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Biological Process

External links

PDB	RCSB:3e43, PDBe:3e43, PDBj:3e43
PDBsum	3e43
PubMed	18762194
UniProt	P17743\|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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