Structure of PDB 3e40 Chain B Binding Site BS01

Receptor Information
>3e40 Chain B (length=241) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKVKREKLVYKFLKENLSDLTFKQYEYLNDLFMK
NPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKNDTADILL
VKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKEFDLFDIN
YLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQ
GFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL
Ligand information
Receptor-Ligand Complex Structure
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PDB3e40 DNA distortion and specificity in a sequence-specific endonuclease.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		N110 D111 K129 T130 S136 A137 F138 P140 N141 S144 Y146 K147 A205 M206 Q207
Binding residue
(residue number reindexed from 1)		N93 D94 K112 T113 S119 A120 F121 P123 N124 S127 Y129 K130 A188 M189 Q190
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:3e40, PDBe:3e40, PDBj:3e40
PDBsum3e40
PubMed18762194
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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