Structure of PDB 3do7 Chain B Binding Site BS01

Receptor Information
>3do7 Chain B (length=293) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYE
GPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNL
GVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMD
LSIVRLRFSAFLRDSDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKT
AGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYA
IVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3do7 NF-kapppaB p52:RelB heterodimer uses different binding modes to recognize different kappaB DNA
Resolution3.05 Å
Binding residue
(original residue number in PDB)		R52 R54 S61 H62
Binding residue
(residue number reindexed from 1)		R16 R18 S25 H26
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3do7, PDBe:3do7, PDBj:3do7
PDBsum3do7
PubMed
UniProtQ00653|NFKB2_HUMAN Nuclear factor NF-kappa-B p100 subunit (Gene Name=NFKB2)

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