Structure of PDB 3cyy Chain B Binding Site BS01
Receptor Information
>3cyy Chain B (length=81) Species:
9606
(Homo sapiens) [
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KPTKVTLVKSAKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKI
NGTVTENMSLTDAKTLIERSKGKLKMVVQRD
Ligand information
>3cyy Chain C (length=9) Species:
10116
(Rattus norvegicus) [
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RPRPDDLEI
Receptor-Ligand Complex Structure
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PDB
3cyy
Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
E197 Y198 L200 R201 L202 V236 N239
Binding residue
(residue number reindexed from 1)
E15 Y16 L18 R19 L20 V54 N57
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3cyy
,
PDBe:3cyy
,
PDBj:3cyy
PDBsum
3cyy
PubMed
18636092
UniProt
Q07157
|ZO1_HUMAN Tight junction protein ZO-1 (Gene Name=TJP1)
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