Structure of PDB 3crc Chain B Binding Site BS01

Receptor Information
>3crc Chain B (length=220) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NQIDRLLTIMQRLWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGEL
GDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERAQHSALDDIPRSLPA
LMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLE
EEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEM
TGVDLETMEEVWQQVARQEI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3crc Chain B Residue 264 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3crc Crystal structure of Escherichia coli MazG, the regulator of nutritional stress response.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		E172 E175 E193 D196
Binding residue
(residue number reindexed from 1)		E131 E134 E152 D155
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.1.8: ATP diphosphatase.
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0047429 nucleoside triphosphate diphosphatase activity
GO:0047693 ATP diphosphatase activity
Biological Process
GO:0006203 dGTP catabolic process
GO:0009267 cellular response to starvation
GO:0046047 TTP catabolic process
GO:0046052 UTP catabolic process
GO:0046061 dATP catabolic process
GO:0046076 dTTP catabolic process
GO:0046081 dUTP catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3crc, PDBe:3crc, PDBj:3crc
PDBsum3crc
PubMed18353782
UniProtP0AEY3|MAZG_ECOLI Nucleoside triphosphate pyrophosphohydrolase (Gene Name=mazG)

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